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MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.
Gene Name: | microsomal triglyceride transfer protein |
Synonyms: | MTTP, ABL, MTP |
Target Sequences: | NM_000253 NP_000244.2 P55157 |
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