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MARCH6 / DOA10

membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase

E3 ubiquitin-protein ligase that promotes ubiquitination of DIO2, leading to its degradation. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May cooperate with UBE2G1.

Gene Name: membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
Synonyms: MARCH6, DOA10, Doa10 homolog, KIAA0597, RING finger protein 176, TEB4, MARCH-VI, Protein TEB-4, RNF176
Target Sequences: NM_005885 NP_005876.2 O60337

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Proteins (1)
Recombinant (1)
MARCH6 / DOA10 (1)
No (1)
GST, N-terminus (1)
Human (1)
Wheat Germ Extract (1)
MARCH6 / DOA10 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).