IL28B

interferon, lambda 3

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

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Products

ELISA Kits (10)

Type

Custom (1)

Sandwich (7)

Sandwich CLIA (2)

Target

IL28B (10)

Reactivity

Human (9)

Mouse (1)

Format

12 x 8-Well Microstrips (1)

96-Well Strip Plate (9)

Publications

No (10)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (4)

Plasma (9)

Serum (9)

Tissue Homogenates (3)

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Human IL28B (CLIA) ELISA Kit - LS-F26382

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.37 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$851

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Human IL28B (Sandwich ELISA) ELISA Kit - LS-F646

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

32 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$534

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Human IL28B (Sandwich ELISA) ELISA Kit - LS-F4455

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$671

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Human IL28B (Sandwich ELISA) ELISA Kit - LS-F11775

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse IL28B (Custom ELISA) ELISA Kit - LS-F19077

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$585

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Human IL28B (CLIA) ELISA Kit - LS-F29041

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

8 - 500 pg/ml

Detection:

Chemiluminescent

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$562

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Human IL28B (Sandwich ELISA) ELISA Kit - LS-F31652

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$624

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Human IL28B (Sandwich ELISA) ELISA Kit - LS-F36206

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human IL28B (Sandwich ELISA) ELISA Kit - LS-F38145

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human IL28B (Sandwich ELISA) ELISA Kit - LS-F38937

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$792

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