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IL13

interleukin 13

IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Gene Name: interleukin 13
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL13, ALRH, BHR1, Interleukin-13, NC30, p600, IL-13, Interleukin 13
Target Sequences: NM_002188 NP_002179.2 P35225

Publications (1)

1
A new heterotopic transplant animal model of intestinal fibrosis. Martin Hausmann, Thomas Rechsteiner, Michaela Caj, Christian Benden, Michael Fried, Annette Boehler, Gerhard Rogler. The Breast : official journal of the European Society of Mastology. 2013 Oct;;19:2302-14. [Full Text Article] [PubMed:24013360] Related Antibodies: LS-B3767.

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IL13 (116)
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IL13 Antibody - Anti-IL-13 antibody IHC of rat spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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IL13 Mouse anti-Rat Monoclonal (5J56) Antibody
Rat
ELISA, Flo, IHC-P
Unconjugated
125 µg/$595
IL13 Antibody - Anti-IL-13 antibody IHC of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IL13 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
IL13 Antibody - Direct ELISA of IL-13 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL13 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
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IL13 Rat anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, SwELISA, WB
Unconjugated
250 µg/$459; 500 µg/$611
IL13 Antibody - IL13 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lung tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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IL13 Rabbit anti-Human Polyclonal (aa118-146) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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IL13 Rat anti-Human Monoclonal (JES10-5A2) Antibody
Human
ELISA, IHC, IHC-Fr, Neut, WB
Unconjugated
100 µg/$434; 500 µg/$866
IL13 Antibody - Immunohistochemistry of paraffin-embedded mouse brain tissue.
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IL13 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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IL13 Mouse anti-Human Monoclonal (Preservative Free) (4C10A7B3) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
IL13 Antibody - BALB/c splenocytes were cultured for 3 days with plate-bound anti-mouse CD3e (clone 145-2C11, ), soluble anti-mouse CD28 (clone 37.51), recombinant mouse IL-2, and recombinant mouse IL-4. Cells were then harvested and restimulated with PMA/Ionomycin in the presence of monensin for 5 hours. Following restimulation, cells were harvested, surface stained with FITC anti-mouse CD4 (clone RM4-5, LS-C106049), fixed and permeabilized, then stained with 0.125 ug PE antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL13 Rat anti-Mouse Monoclonal (PE) (13A) Antibody
Mouse
Flo
PE Conjugated
25 Tests/$279
IL13 Antibody - Immunohistochemistry of paraffin-embedded human lung tissue at dilution of 1:100
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IL13 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
IL13 Antibody
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IL13 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
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IL13 Mouse anti-Human Monoclonal (3H7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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IL13 Rat anti-Human Monoclonal (JES10-35G12) Antibody
Human
ELISA
Unconjugated
0.5 mg/$534
IL13 Antibody - Western blot analysis of extracts of NCI-H460 cells, using IL13 antibody. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
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IL13 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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IL13 Mouse anti-Human Monoclonal (2B5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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IL13 Rat anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$568
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IL13 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated
100 µl/$860
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IL13 Mouse anti-Human Monoclonal (Preservative Free) (15) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$286; 100 µl/$435
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IL13 Mouse anti-Human Monoclonal (Preservative Free) (02) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
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IL13 Rat anti-Human Monoclonal (SB126d) Antibody
Human
ELISA
Unconjugated
0.5 mg/$457
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IL13 Rabbit anti-Human Polyclonal (aa118-146) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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IL13 Rabbit anti-Human Polyclonal (aa118-146) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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IL13 Rabbit anti-Human Polyclonal (aa118-146) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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IL13 Rabbit anti-Human Polyclonal (aa118-146) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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IL13 Rat anti-Human Monoclonal (Azide-free) Antibody
Human
ELISA, Flo, IF, Neut, SwELISA, WB
Unconjugated, Azide-free
500 µg/$611
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).