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HK2 / Hexokinase 2

hexokinase 2

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Gene Name: hexokinase 2
Family/Subfamily: Non-protein Kinase , Hexokinase
Synonyms: HK2, Hexokinase II, Hexokinase type II, Hexokinase-2, muscle, HK II, HXK2, Hexokinase-2, Muscle form hexokinase, Hexokinase 2, HKII, Hxk 2
Target Sequences: NM_000189 NP_000180.2 P52789

Publications (2)

1
p53 Protects Cells from Death at the Heatstroke Threshold Temperature. Lu Gong, Qinghe Zhang, Xiao Pan, Shuming Chen, Lina Yang, Bin Liu, Weijun Yang, Luyang Yu, Zhi-Xiong Xiao, Xin-Hua Feng, Haihe Wang, Zhi-Min Yuan, Jinrong Peng, Wei-Qiang Tan, Jun Chen. Cell reports. 2019 Dec;29:3693-3707e5. [Full Text Article] [PubMed:31825845] Related Antibodies: LS-B3571.
2
Cdh1-mediated Skp2 degradation by dioscin reprogrammes aerobic glycolysis and inhibits colorectal cancer cells growth. Li Zhou, Xinfang Yu, Ming Li, Guanghui Gong, Wenbin Liu, Tian Li, Huilan Zuo, Wei Li, Feng Gao, Haidan Liu. EBioMedicine. 2020 Jan;51:102570. [Full Text Article] [PubMed:31806563] [PMC:PMC7000337] Related Antibodies: LS-C404653.

☰ Filters
Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
HK2 / Hexokinase 2 (9)
No (9)
GST (1)
GST, N-terminus (1)
His (2)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (7)
Mouse (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
Biologically active (1)
HK2 / Hexokinase 2 Protein
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E. coli
His
Biologically active
100 µg/$511; 500 µg/$1,348; 20 µg/$311
HK2 / Hexokinase 2 Protein - 12.5% SDS-PAGE of human HK2 stained with Coomassie Blue
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Wheat Germ Extract
GST
128.8 kDa
10 µg/$479; 25 µg/$670
HK2 / Hexokinase 2 Protein - Purified recombinant protein HK2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
102.2 kDa
20 µg/$1,107
HK2 / Hexokinase 2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
2 µg/$439
HK2 / Hexokinase 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
102.2 kDa
20 µg/$150
HK2 / Hexokinase 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
102.2 kDa
100 µg/$494
HK2 / Hexokinase 2 Protein - Recombinant Hexokinase 2 By SDS-PAGE
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E. coli
His
34.5 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
HK2 / Hexokinase 2 Protein - Recombinant Hexokinase 2 By SDS-PAGE
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E. coli
His-T7
26.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
HK2 / Hexokinase 2 Protein - Recombinant Hexokinase 2 By SDS-PAGE
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E. coli
His-GST
56.4 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).