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Unfortunately, the antibody LS-C209099 is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



GRHPR / Glyoxylate Reductase Antibodies

glyoxylate reductase/hydroxypyruvate reductase

Gene Name: glyoxylate reductase/hydroxypyruvate reductase
Synonyms: GRHPR Antibody, GLYD Antibody, Glycerate-2-dehydrogenase Antibody, GLXR Antibody, PH2 Antibody
Target Sequences: NM_012203 NP_036335.1 Q9UBQ7
 GRHPR / Glyoxylate Reductase Feature Table

GRHPR / Glyoxylate Reductase Antibodies (11)

Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
GRHPR / Glyoxylate Reductase Mouse IgG1 Monoclonal 1H8 Unconjugated Human IHC-P, WB, Flo No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody (clone 1H8) LS-C172360
IHC Image
IHC Image
Mouse Monoclonal [clone 1H8] (IgG1) to Human GRHPR / Glyoxylate Reductase
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
GRHPR / Glyoxylate Reductase Mouse IgG1 Monoclonal 10A3 Unconjugated Human IHC-P, WB, Flo No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody (clone 10A3) LS-C172482
IHC Image
IHC Image
Mouse Monoclonal [clone 10A3] (IgG1) to Human GRHPR / Glyoxylate Reductase
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
GRHPR / Glyoxylate Reductase Mouse IgG2b Monoclonal 4H2 Unconjugated Human WB, Flo No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody (clone 4H2) LS-C115835
Flo Image
WB Image
Mouse Monoclonal [clone 4H2] (IgG2b) to Human GRHPR / Glyoxylate Reductase
Human
Western blot, Flow Cytometry
Unconjugated
GRHPR / Glyoxylate Reductase Mouse IgG1 Monoclonal 9G2 Unconjugated Human WB, Flo No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody (clone 9G2) LS-C172481
Flo Image
WB Image
Mouse Monoclonal [clone 9G2] (IgG1) to Human GRHPR / Glyoxylate Reductase
Human
Western blot, Flow Cytometry
Unconjugated
GRHPR / Glyoxylate Reductase Rabbit IgG Polyclonal Unconjugated Human, Orangutan, Gibbon, Dog, Pig WB aa38-87 No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody (aa38-87) LS-C81216
WB Image
Rabbit Polyclonal (IgG) to Human GRHPR / Glyoxylate Reductase
Human, Orangutan, Gibbon, Dog, Pig
Western blot
Unconjugated
GRHPR / Glyoxylate Reductase Rabbit IgG Polyclonal Biotin Conjugated Spinach WB, ELISA, ID, IE No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody (Biotin) LS-C185078
Rabbit Polyclonal (IgG) to Spinach GRHPR / Glyoxylate Reductase
Spinach
Western blot, ELISA, Immunodiffusion, Immunoelectrophoresis
Biotin Conjugated
GRHPR / Glyoxylate Reductase Rabbit IgG Polyclonal Unconjugated Spinach WB, ELISA, ID, IE No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody LS-C185077
Rabbit Polyclonal (IgG) to Spinach GRHPR / Glyoxylate Reductase
Spinach
Western blot, ELISA, Immunodiffusion, Immunoelectrophoresis
Unconjugated
GRHPR / Glyoxylate Reductase Rabbit IgG Polyclonal Unconjugated Spinach WB, ELISA, ID, IE No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody LS-C185076
Rabbit Polyclonal (IgG) to Spinach GRHPR / Glyoxylate Reductase
Spinach
Western blot, ELISA, Immunodiffusion, Immunoelectrophoresis
Unconjugated
GRHPR / Glyoxylate Reductase Mouse IgG1 Monoclonal 10C402 Unconjugated, Azide-free Human WB, ELISA aa1-329 No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody (aa1-329, clone 10C402, Azide-free) LS-C183658
Mouse Monoclonal [clone 10C402] (IgG1) to Human GRHPR / Glyoxylate Reductase
Human
Western blot, ELISA
Unconjugated, Azide-free
GRHPR / Glyoxylate Reductase Mouse IgG1,k Monoclonal 4E6-1F2 Unconjugated Human WB, ELISA No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody (clone 4E6-1F2) LS-C308119
Mouse Monoclonal [clone 4E6-1F2] (IgG1,k) to Human GRHPR / Glyoxylate Reductase
Human
Western blot, ELISA
Unconjugated
GRHPR / Glyoxylate Reductase Rabbit IgG Polyclonal Unconjugated Human WB No Primary
Anti-GRHPR / Glyoxylate Reductase Antibody LS-C310519
Rabbit Polyclonal (IgG) to Human GRHPR / Glyoxylate Reductase
Human
Western blot
Unconjugated

GRHPR / Glyoxylate Reductase Feature Table


Feature Type Location Details
catalytic activity 1 - 328 D-glycerate + NAD(P)(+) = hydroxypyruvate + NAD(P)H.
catalytic activity 1 - 328 Glycolate + NADP(+) = glyoxylate + NADPH.
Disease 1 - 328 Defects in GRHPR are the cause of hyperoxaluria primary type 2 (HP2) [MIM:260000]; also known as primary hyperoxaluria type II (PH2). HP2 is a disorder where the main clinical manifestation is calcium oxalate nephrolithiasis though chronic as well as terminal renal insufficiency has been described. It is characterized by an elevated urinary excretion of oxalate and L- glycerate.
Function 1 - 328 Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
interaction 1 - 328 O15116:LSM1; NbExp=1; IntAct=EBI-372445, EBI-347619;
sequence caution 1 - 328 Sequence=AAD54066.1; Type=Frameshift; Positions=109, 137; Sequence=AAG39286.1; Type=Frameshift; Positions=237;
Similarity 1 - 328 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Subunit 1 - 328 Homodimer.
Tissue Specificity 1 - 328 Ubiquitous. Most abundantly expressed in the liver.
web resource 1 - 328 Name=GeneReviews; URL="http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/GRHPR";
arrayexpress 1 - 328 Q9UBQ7
bgee 1 - 328 Q9UBQ7
brenda 1 - 328 1.1.1.79
cleanex 1 - 328 HS_GRHPR
ctd 1 - 328 9380
doi 1 - 328 10
embl 1 - 328 AF113215
embl 1 - 328 AF113251
embl 1 - 328 AF134895
embl 1 - 328 AF146018
embl 1 - 328 AF146689
embl 1 - 328 BC000605
ensembl 1 - 328 ENST00000318158
gene3d 1 - 328 G3DSA:3.40.50.720
genecards 1 - 328 GC09P037412
geneid 1 - 328 9380
genevestigator 1 - 328 Q9UBQ7
germonline 1 - 328 ENSG00000137106
go 1 - 328 GO:0005515
go 1 - 328 GO:0005737
go 1 - 328 GO:0007588
go 1 - 328 GO:0008465
go 1 - 328 GO:0016618
go 1 - 328 GO:0030267
go 1 - 328 GO:0046487
go 1 - 328 GO:0051287
go 1 - 328 GO:0055114
h-invdb 1 - 328 HIX0008036
hgnc 1 - 328 HGNC:4570
hovergen 1 - 328 HBG051838
hpa 1 - 328 HPA022971
intact 1 - 328 Q9UBQ7
interpro 1 - 328 IPR006139
interpro 1 - 328 IPR006140
interpro 1 - 328 IPR016040
ipi 1 - 328 IPI00037448
kegg 1 - 328 hsa:9380
medline 1 - 328 20145426
medline 1 - 328 99415747
medline 1 - 328 99453739
mim 1 - 328 260000
mim 1 - 328 604296
nextbio 1 - 328 35148
nmpdr 1 - 328 fig|9606.3.peg.31284
oma 1 - 328 RGDVVNQ
orphanet 1 - 328 416
orthodb 1 - 328 EOG93N9ZD
pdb 1 - 328 2GCG
pdb 1 - 328 2H1S
pdb 1 - 328 2Q50
pdbsum 1 - 328 2GCG
pdbsum 1 - 328 2H1S
pdbsum 1 - 328 2Q50
pfam 1 - 328 PF00389
pfam 1 - 328 PF02826
pharmgkb 1 - 328 PA28965
phylomedb 1 - 328 Q9UBQ7
pir 1 - 328 JC7190
pride 1 - 328 Q9UBQ7
prosite 1 - 328 PS00065
prosite 1 - 328 PS00670
prosite 1 - 328 PS00671
proteinmodelportal 1 - 328 Q9UBQ7
pubmed 1 - 328 10484776
pubmed 1 - 328 10524214
pubmed 1 - 328 10679197
pubmed 1 - 328 15489334
pubmed 1 - 328 16756993
reactome 1 - 328 REACT_13
refseq 1 - 328 NP_036335.1
reproduction-2dpage 1 - 328 IPI00037448
string 1 - 328 Q9UBQ7
ucd-2dpage 1 - 328 Q9UBQ7
ucsc 1 - 328 uc003zzu.1
unigene 1 - 328 Hs.155742
alt_frame; mrna 1 - 328 AAD54066.1
alt_frame; mrna 1 - 328 AAG39286.1
act_site 293 - 293 Proton donor
binding 217 - 217 NADP
binding 243 - 243 NADP; via carbonyl oxygen
binding 245 - 245 Substrate
binding 269 - 269 Substrate
binding 295 - 295 NADP; via amide nitrogen
chain 1 - 328 Glyoxylate reductase/hydroxypyruvate reductase. /FTId=PRO_0000075944.
np_bind 162 - 164 NADP
np_bind 185 - 188 NADP
region 83 - 84 Substrate binding
region 293 - 296 Substrate binding
site 274 - 274 Raises pKa of active site His
variant 170 - 170 R -> Q (in dbSNP:rs12002324) /FTId=VAR_032762.
keyword 1 - 328 3D-structure
keyword 1 - 328 Complete proteome
keyword 1 - 328 NADP
keyword 1 - 328 Oxidoreductase
keyword 1 - 328 Polymorphism
Molecular Weight 1 - 328 35668
1 hit 1 - 328 PF00389
1 hit 1 - 328 PF02826
1 hit 1 - 328 PS00671
false_neg 1 - 328 PS00065
false_neg 1 - 328 PS00670

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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