E6AP / UBE3A

ubiquitin protein ligase E3A

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Catalyzes the high-risk human papilloma virus E6-mediated ubiquitination of p53/TP53, contributing to the neoplastic progression of cells infected by these viruses. Additionally, may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. Finally, UBE3A also promotes its own degradation in vivo.

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Antibodies (39)

Type

Primary (39)

Target

E6AP / UBE3A (39)

Reactivity

Human (39)

Mouse (9)

Rat (9)

Bat (6)

Bovine (3)

Chicken (3)

Chimpanzee (6)

Dog (3)

Drosophila (3)

Gibbon (6)

Guinea pig (3)

Horse (3)

Monkey (6)

Orangutan (6)

Pig (3)

Rabbit (3)

Zebrafish (6)

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Application

IHC (14)

IHC-P (8)

WB (32)

Flo (1)

ELISA (9)

ICC (2)

IF (5)

IP (2)

Host

rabbit (38)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (19)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (38)

Clone

2F6 (1)

Format

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (5)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (2)

Preservative Free (1)

Unconjugated (18)

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Epitope

aa158-407 (8)

aa836-865 (7)

C-Terminus (4)

aa180-229 (4)

aa1-851 (1)

aa34-422 (1)

aa342-585 (1)

aa400-450 (1)

aa75-125 (1)

Publications

No (39)

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E6AP / UBE3A Antibody (clone 2F6) LS-C133508

Antibody:

E6AP / UBE3A Mouse anti-Human Monoclonal (2F6) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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E6AP / UBE3A Antibody LS-C482305

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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E6AP / UBE3A Antibody (aa836-865) LS-C99579

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa836-865) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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E6AP / UBE3A Antibody (aa180-229) LS-C110728

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa180-229) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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E6AP / UBE3A Antibody (C-Terminus) LS-C110729

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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E6AP / UBE3A Antibody LS-C408348

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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E6AP / UBE3A Antibody (aa1-851) LS-C19980

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa1-851) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$450

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IHC-plus™ E6AP / UBE3A Antibody (aa342-585) LS-B14302

(4.0) Rating

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa342-585) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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E6AP / UBE3A Antibody LS-C815077

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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E6AP / UBE3A Antibody (Preservative Free) LS-C814803

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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E6AP / UBE3A Antibody (aa836-865) LS-C123428

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa836-865) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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E6AP / UBE3A Antibody (aa836-865, Biotin) LS-C225266

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa836-865) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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E6AP / UBE3A Antibody (aa836-865, FITC) LS-C225267

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa836-865) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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E6AP / UBE3A Antibody (aa836-865, APC) LS-C225265

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa836-865) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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E6AP / UBE3A Antibody (aa836-865, Azide-free, HRP) LS-C225268

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa836-865) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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E6AP / UBE3A Antibody (aa836-865, PE) LS-C225269

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa836-865) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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E6AP / UBE3A Antibody LS-C661394

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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E6AP / UBE3A Antibody LS-C771586

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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E6AP / UBE3A Antibody LS-C674970

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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E6AP / UBE3A Antibody (aa34-422) LS-C311495

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa34-422) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$450

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E6AP / UBE3A Antibody (aa400-450) LS-C287249

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa400-450) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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E6AP / UBE3A Antibody (aa75-125) LS-C287248

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa75-125) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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E6AP / UBE3A Antibody (aa158-407) LS-C296911

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa158-407) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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E6AP / UBE3A Antibody (aa158-407, Biotin) LS-C685422

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa158-407) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279

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E6AP / UBE3A Antibody (aa158-407, FITC) LS-C691896

Antibody:

E6AP / UBE3A Rabbit anti-Human Polyclonal (aa158-407) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$341; 200 µl/$397; 500 µl/$583; 1 ml/$715; 2 ml/$953; 5 ml/$1,628

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

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