CYP1B1

cytochrome P450, family 1, subfamily B, polypeptide 1

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes 17beta-estradiol to the carcinogenic 4-hydroxy derivative, and a variety of procarcinogenic compounds to their activated forms, including polycyclic aromatic hydrocarbons. Promotes angiogenesis by removing cellular oxygenation products, thereby decreasing oxidative stress, release of antiangiogenic factor THBS2, then allowing endothelial cells migration, cell adhesion and capillary morphogenesis. These changes are concommitant with the endothelial nitric oxide synthase activity and nitric oxide synthesis. Plays an important role in the regulation of perivascular cell proliferation, migration, and survival through modulation of the intracellular oxidative state and NF-kappa-B expression and/or activity, during angiogenesis. Contributes to oxidative homeostasis and ultrastructural organization and function of trabecular meshwork tissue through modulation of POSTN expression.

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Products

ELISA Kits (16)

Type

Competitive EIA (1)

Custom (2)

Sandwich (12)

Sandwich CLIA (1)

Target

CYP1B1 (16)

Reactivity

Human (5)

Mouse (1)

Rat (4)

Chicken (1)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (13)

Publications

No (16)

Sample Type

Cell Lysates (2)

Plasma (6)

Serum (6)

Tissue Homogenates (4)

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Human CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F20912

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Chicken CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F43078

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

7.813 - 500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F43079

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Monkey CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F43080

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F43081

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F43082

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

7.813 - 500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Sheep CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F43083

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

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Mouse CYP1B1 (Custom ELISA) ELISA Kit - LS-F15609

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human CYP1B1 (Custom ELISA) ELISA Kit - LS-F15610

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Rat CYP1B1 (Competitive EIA) ELISA Kit - LS-F11189

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F25418

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$783

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Human CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F7446

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

Select

Human CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F35023

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F22817

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human CYP1B1 (CLIA) ELISA Kit - LS-F29346

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Rat CYP1B1 (Sandwich ELISA) ELISA Kit - LS-F35835

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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