Complement C5

complement component 5

Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes (PubMed:8182049). C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.

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Products

ELISA Kits (28)

Type

Competitive EIA (1)

Custom (3)

Sandwich (24)

Target

Complement C5 (28)

Reactivity

Human (7)

Mouse (9)

Rat (4)

Chicken (1)

Guinea pig (1)

Monkey (2)

Pig (1)

Porcine (1)

Sheep (1)

Format

96-Well Microplate (4)

96-Well Strip Plate (24)

Publications

No (28)

Sample Type

Cell Culture Supernatants (3)

Plasma (24)

Serum (24)

Tissue Homogenates (5)

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Human Complement C5 (Sandwich ELISA) ELISA Kit - LS-F5788

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.12 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$798

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Mouse Complement C5 (Sandwich ELISA) ELISA Kit - LS-F21340

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse Complement C5 (Sandwich ELISA) ELISA Kit - LS-F24781

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$590

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Human Complement C5 (Sandwich ELISA) ELISA Kit - LS-F24462

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$632

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Rat Complement C5 (Sandwich ELISA) ELISA Kit - LS-F5840

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$750

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Rat Complement C5 (Sandwich ELISA) ELISA Kit - LS-F34563

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse Complement C5 (Sandwich ELISA) ELISA Kit - LS-F6286

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

12.5 - 800 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$715

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Pig Complement C5 (Sandwich ELISA) ELISA Kit - LS-F18924

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse Complement C5 (Sandwich ELISA) ELISA Kit - LS-F32840

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Monkey Complement C5 (Sandwich ELISA) ELISA Kit - LS-F42675

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Guinea pig Complement C5 (Sandwich ELISA) ELISA Kit - LS-F42674

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Porcine Complement C5 (Sandwich ELISA) ELISA Kit - LS-F42676

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Bovine Complement C5 (Custom ELISA) ELISA Kit - LS-F18925

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat Complement C5 (Custom ELISA) ELISA Kit - LS-F18926

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Human Complement C5 (Custom ELISA) ELISA Kit - LS-F18927

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$585

Select

Mouse Complement C5 (Sandwich ELISA) ELISA Kit - LS-F11163

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Mouse Complement C5 (Sandwich ELISA) ELISA Kit - LS-F39643

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$784

Select

Sheep Complement C5 (Sandwich ELISA) ELISA Kit - LS-F42677

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

39.063 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$691

Select

Chicken Complement C5 (Sandwich ELISA) ELISA Kit - LS-F42673

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Human Complement C5 (Sandwich ELISA) ELISA Kit - LS-F26753

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

10 - 250 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Rat Complement C5 (Sandwich ELISA) ELISA Kit - LS-F27385

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

25 - 500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Human Complement C5 (Sandwich ELISA) ELISA Kit - LS-F22730

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Mouse Complement C5 (Competitive EIA) ELISA Kit - LS-F28256

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

50 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Human Complement C5 (Sandwich ELISA) ELISA Kit - LS-F2794

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

Select

Monkey Complement C5 (Sandwich ELISA) ELISA Kit - LS-F52846

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$968

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