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CDH15 / M Cadherin is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.
Gene Name: | cadherin 15, type 1, M-cadherin (myotubule) |
Family/Subfamily: | Cadherin , not assigned-Cadherin |
Synonyms: | CDH15, Cadherin-14, Cadherin-3, CDH14, M-cadherin, Muscle cadherin, MRD3, Muscle-cadherin, M Cadherin, Cadherin-15, CDHM, MCAD, Myotubule-cadherin |
Target Sequences: | NM_004933 NP_004924.1 P55291 |
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