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CD3

The CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3gamma chain, a CD3delta chain, and two CD3epsilon chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the zeta-chain to generate an activation signal in T lymphocytes. The TCR, zeta-chain, and CD3 molecules together comprise the TCR complex.

CD3 Target Details

Target Name: CD3

Publications (7)

1
Blocking of monocyte-associated B7-H1 (CD274) enhances HCV-specific T cell immunity in chronic hepatitis C infection. Jeong HY, Lee YJ, Seo SK, Lee SW, Park SJ, Lee JN, Sohn HS, Yao S, Chen L, Choi I. Journal of leukocyte biology. 2008 83:755-64. [PubMed:18086898] Related Antibodies: LS-C41100.
2
Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination. Thakral D, Dobbins J, Devine L, Kavathas PB. Journal of immunology (Baltimore, Md. : 1950). 2008 180:7431-42. [PubMed:18490743]
3
Ligand-independent exhaustion of killer immunoglobulin-like receptor-positive CD8+ T cells in human immunodeficiency virus type 1 infection. Alter G, Rihn S, Streeck H, Teigen N, Piechocka-Trocha A, Moss K, Cohen K, Meier A, Pereyra F, Walker B, Altfeld M. Journal of virology. 2008 82:9668-77. [PubMed:18579582] [PMC:PMC2546972] Related Antibodies: LS-C41100.
4
Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions. Manevich-Mendelson E, Feigelson SW, Pasvolsky R, Aker M, Grabovsky V, Shulman Z, Kilic SS, Rosenthal-Allieri MA, Ben-Dor S, Mory A, Bernard A, Moser M, Etzioni A, Alon R. Blood. 2009 114:2344-53. [PubMed:19617577] Related Antibodies: LS-C41100.
5
High-resolution imaging of the immunological synapse and T-cell receptor microclustering through microfabricated substrates. Biggs MJ, Milone MC, Santos LC, Gondarenko A, Wind SJ. Journal of the Royal Society, Interface / the Royal Society. 2011 8:1462-71. [PubMed:21490003] [PMC:PMC3163423] Related Antibodies: LS-C41100.
6
Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo. Luckashenak N, Whe A, Breit K, Brakebusch C, Brocker T. Journal of immunology (Baltimore, Md. : 1950). 2013 190:27-35. [PubMed:23209325]
7
Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4. Lu N, Li Y, Zhang Z, Xing J, Sun Y, Yao S, Chen L. Nature communications. 2018 February;9:742. (Human) [Full Text Article] [PubMed:29467366] [PMC:PMC5821868] Related Antibodies: LS-C351533.
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ELISA Kits (7)
Competitive EIA (1)
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CD3 (7)
Mouse (4)
Rat (3)
12 x 8-Well Microstrips (2)
96-Well Microplate (2)
96-Well Strip Plate (3)
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Plasma (7)
Serum (7)
Tissue Homogenates (2)
CD3 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.39 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CD3 ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
CD3 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
78.125 - 5000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
CD3 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Rat
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
CD3 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.391 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CD3 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CD3 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).