Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CAMK2B / CaMKII Beta

calcium/calmodulin-dependent protein kinase II beta

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.

Gene Name: calcium/calmodulin-dependent protein kinase II beta
Family/Subfamily: Protein Kinase , CAMK2
Synonyms: CAMK2B, Beta-subunit of CaMK II, Cam kinase II beta, CaMK IIbeta, CaM-kinase II beta chain, CAMKB, Beta CaMK II, CaM kinase II beta subunit, CaM kinase II subunit beta, CaM kinase IIbeta, CAM2, Camk ii beta, CAMK2, CaMKII beta, CaMK-II subunit beta, CaMKIIbeta
Target Sequences: NM_001220 NP_001211.3 Q13554

Publications (2)

1
CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca2+ Signals during LTP Induction, but Not Maintenance. Chang JY, Parra-Bueno P, Laviv T, Szatmari EM, Lee SR, Yasuda R. Neuron. 2017 May;94:800-808. (Rat) [Full Text Article] [PubMed:28521133] [PMC:PMC5573161] Related Antibodies: LS-B5767.
2
Generation and behavior characterization of CaMKII beta knockout mice. Bachstetter AD, Webster SJ, Tu T, Goulding DS, Haiech J, Watterson DM, Van Eldik LJ. PloS one. 9:e105191. [Full Text Article] [PubMed:25127391] [PMC:PMC4134274] Related Antibodies: LS-B5767.

☰ Filters
Products
ELISA Kits (2)
Cell-Based (1)
Sandwich (1)
CAMK2B / CaMKII Beta (2)
Human (2)
Mouse (1)
Rat (1)
96-Well Microplate (1)
96-Well Strip Plate (1)
No (2)
Adherent Cell Cultures (1)
Cell Lysates (1)
Tissue Homogenates (1)
CAMK2B / CaMKII Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
CAMK2B / CaMKII Beta ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
Viewing 1-2 of 2 product results


Filtered By:
Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).