ALK2 / ACVR1

activin A receptor, type I

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

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Products

Proteins (18)

Type

Over-Expression Lysate (4)

Recombinant (14)

Target

ALK2 / ACVR1 (18)

Publications

No (18)

Tag

6His, C-terminus (2)

Fc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (3)

His-GST (1)

His-Human IgG1 Fc (1)

Human IgG1 Fc, C-terminus (2)

Myc-DDK (Flag) (6)

Species

Human (13)

Mouse (2)

Rat (1)

Source

293T Cells (2)

Baculovirus (1)

E. coli (3)

HEK 293 Cells (4)

Human (1)

Human Cells (4)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (7)

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Human ALK2 / ACVR1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66938

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55 kDa

Price:

20 µg/$1,107

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Human ALK2 / ACVR1 Protein (Recombinant His-Human IgG1 Fc) (Met1-Val124) - LS-G97149

Source:

Human Cells

Tag:

His-Human IgG1 Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

39.6 kDa

Price:

200 µg/$1,148

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Rat ALK2 / ACVR1 Protein (Recombinant Human IgG1 Fc, C-terminus) (Met1-Glu123) - LS-G98311

Source:

Human Cells

Tag:

Human IgG1 Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.5 kDa

Price:

200 µg/$1,148

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Mouse ALK2 / ACVR1 Protein (Recombinant Human IgG1 Fc, C-terminus) (Met1-Glu123) - LS-G98694

Source:

Human Cells

Tag:

Human IgG1 Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

40 kDa

Price:

200 µg/$1,148

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Human ALK2 / ACVR1 Protein (Recombinant Fc, C-terminus) - LS-G146106

Source:

Human

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.2 kDa

Price:

10 µg/$262; 50 µg/$363

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Human ALK2 / ACVR1 Protein (Recombinant GST) (Full Length) - LS-G27351

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

81.73 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ALK2 / ACVR1 Protein (Recombinant GST, N-terminus) (aa21-120) - LS-G57690

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ALK2 / ACVR1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66939

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55 kDa

Price:

20 µg/$1,107

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Human ALK2 / ACVR1 Protein (Recombinant His) (Met1-Val124) - LS-G98509

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.8 kDa

Price:

100 µg/$793; 1 mg/$4,191

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Human ALK2 / ACVR1 Protein (Recombinant 6His, C-terminus) (Met21-Val124) - LS-G39331

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.6kD

Price:

10 µg/$248; 50 µg/$288; 500 µg/$785; 1 mg/$1,203

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Human ALK2 / ACVR1 Protein (Recombinant 6His, C-terminus) (Met21-Val124) - LS-G138611

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.6 kDa

Price:

10 µg/$248; 50 µg/$288

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ALK2 / ACVR1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118857

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.15 kDa

Price:

100 µg/$494

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Human ALK2 / ACVR1 Protein (Recombinant His) (aa208-340) - LS-G13155

Source:

E. coli

Tag:

His

Molecular Weight:

16.7 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human ALK2 / ACVR1 Protein (Recombinant His-GST) (aa208-340) - LS-G13156

Source:

E. coli

Tag:

His-GST

Molecular Weight:

47.2 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Mouse ALK2 / ACVR1 Protein (Recombinant His) (aa208-340) - LS-G13159

Source:

E. coli

Tag:

His

Molecular Weight:

16.7 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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ALK2 / ACVR1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124225

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.15 kDa

Price:

100 µg/$494

Select

Human ALK2 / ACVR1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78773

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.15 kDa

Price:

20 µg/$150

Select

Human ALK2 / ACVR1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78774

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.15 kDa

Price:

20 µg/$150

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