Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (800) 227-6666


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
PathPlusTM CD95 / FAS Antibodies
FAS receptor (CD95, APO-1) is a transmembrane TNF death receptor that induces apoptosis via FAS ligand binding and is centrally involved in the regulation of programmed cell death. FAS receptor and its ligand FASLG are implicated in the pathogenesis of a number of cancers and immune diseases such as multiple sclerosis. FAS also plays a role in apoptotic cell loss in neurodegenerative diseases. Furthermore, it is upregulated and participates in phenylalanine-induced cell death in cortical neurons in patients with phenylalanine hydroxylase mutations, leading to childhood mental retardation. In immunohistochemistry, FAS has membranous and also secretory positivity at variable levels in most tissues throughout the body. References: Cell Death and Differentiation. 11 Suppl 1 (Suppl 1): S23–7, PMID: 15143352; Nature. 465 (7297): 492–6, PMID: 20505730; PLoS One. 2013 Aug 7;8(8):e71553, PMID: 23940767; Lab Invest. 1998 Apr;78(4):401-11, PMID: 9564885;

1 PathPlusTM Antibody
☰ Filters
Antibodies (1)
Primary (1)
CD95 / FAS (1)
Human (1)
Mouse (1)
Rat (1)
IHC-P (1)
WB (1)
rabbit (1)
Product Group
PathPlus Cancer (1)
polyclonal pc (1)
Unconjugated (1)
C-Terminus (1)
No (1)
CD95 / FAS Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
CD95 / FAS Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
Viewing 1-1 of 1 product results