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Catalog Number Size Price
LS-A1184-50 50 µg (1 mg/ml) $440 
GPER1 / GPR30 Antibody - Anti-GPER1 / GPR30 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPER1 / GPR30 Antibody - Prostate, adenocarcinoma
GPER1 / GPR30 Antibody - Lung, non small cell carcinoma
GPER1 / GPR30 Antibody - Anti-GPER1 / GPR30 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPER1 / GPR30 Antibody - Anti-GPER1 / GPR30 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPER1 / GPR30 Antibody - Anti-GPR30 antibody IHC of human breast carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPER1 / GPR30 Antibody - Anti-GPER1 / GPR30 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPER1 / GPR30 Antibody - Prostate, adenocarcinoma
GPER1 / GPR30 Antibody - Lung, non small cell carcinoma
GPER1 / GPR30 Antibody - Anti-GPER1 / GPR30 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPER1 / GPR30 Antibody - Anti-GPER1 / GPR30 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPER1 / GPR30 Antibody - Anti-GPR30 antibody IHC of human breast carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human GPER1 / GPR30 Antibody (Extracellular Domain, IHC, IF) LS‑A1184

PathPlus™ Polyclonal Rabbit anti‑Human GPER1 / GPR30 Antibody (Extracellular Domain, IHC, IF) LS‑A1184

Antibody:
GPER1 / GPR30 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P, IF
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-A1184-50

Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
GPER1 / GPR30 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P, IF
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
G-protein coupled estrogen receptor 1 (GPER1) promotes neuritogenesis in developing hippocampal neurons. It plays a role in acute neuroprotection against NMDA-induced excitotoxic neuronal death and increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons. GPER1 inhibits mature adipocyte differentiation and lipid accumulation, and is involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells. It also functions as a receptor for aldosterone, mediating rapid regulation of vascular contractibility through the PI3K/ERK signaling pathway. Finally, it is implicated in cancer progression. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GPER1 / GPR30
Synonyms
GPER1 | CMKRL2 | CEPR | FEG-1 | G-protein coupled receptor 30 | G protein-coupled receptor 30 | GPCR-Br | GPER | Heptahelix receptor | LERGU | LyGPR | MER | GPR30 | IL8-related receptor DRY12 | LERGU2 | Chemokine receptor-like 2 | DRY12 | Membrane estrogen receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from human GPR30. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey, Marmoset, Rabbit (94%); Mouse, Rat, Dog, Bat, Bovine, Hamster, Elephant, Panda, Horse, Opossum, Turkey, Zebra finch, Chicken, Platypus, Xenopus, Pufferfish, Zebrafish, Stickleback (88%); Seabass (81%).
Epitope
Extracellular Domain
Specificity
Human GPR30. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (41 - 62 µg/ml)
  • Immunofluorescence
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GPER1 / GPR30
Q99527 NM_001505 NP_001496.1

Validation

GPER1 / GPR30 Antibody - Anti-GPER1 / GPR30 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPER1 / GPR30 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPER1 / GPR30 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPER1 / GPR30 Antibody - Prostate, adenocarcinoma
Prostate, adenocarcinoma
Prostate, adenocarcinoma

GPER1 / GPR30 Antibody - Lung, non small cell carcinoma
Lung, non small cell carcinoma
Lung, non small cell carcinoma

GPER1 / GPR30 Antibody - Anti-GPER1 / GPR30 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPER1 / GPR30 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPER1 / GPR30 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPER1 / GPR30 Antibody - Anti-GPER1 / GPR30 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPER1 / GPR30 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPER1 / GPR30 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPER1 / GPR30 Antibody - Anti-GPR30 antibody IHC of human breast carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR30 antibody IHC of human breast carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR30 antibody IHC of human breast carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ GPER1 / GPR30 Antibody (Extracellular Domain) for IHC, IF/Immunofluorescence LS-A1184 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)

Publications (1)

Stallion spermatozoa: putative target of estrogens; presence of the estrogen receptors ESR1, ESR2 and identification of the estrogen-membrane receptor GPER. Arkoun B, Gautier C, Delalande C, Barrier-Battut I, Gu[Character e9]non I, Goux D, Boura[Character ef]ma-Lelong H. General and comparative endocrinology. 2014 May;200:35-43.

Customer Reviews (0)


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Requested From: United States
Date Requested: 10/31/2024