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| Catalog Number | Size | Price |
|---|---|---|
| LS-B11003-100 | 100 µg (1 mg/ml) | $485 |
IHC‑plus™ Monoclonal Mouse anti‑Rabbit GAPDH Antibody (clone 6C5, IHC, IF, WB) LS‑B11003
IHC‑plus™ Monoclonal Mouse anti‑Rabbit GAPDH Antibody (clone 6C5, IHC, IF, WB) LS‑B11003
Note: This antibody replaces LS-C188573
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
GAPDH antibody LS-B11003 is an unconjugated mouse monoclonal antibody to rabbit GAPDH. Validated for ELISA, IF, IHC, IP and WB.
Target
Rabbit GAPDH
Synonyms
GAPDH | A1 40 kd subunit | Activator 1 40 kd subunit | G3PD | GAPD | G3pdh | Rfc40 | Rf-c 40 kd subunit
Host
Mouse
Reactivity
Rabbit
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
6C5
Purification
Protein A purified
Modifications
Unmodified
Immunogen
Rabbit muscle GAPDH
Specificity
Recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyze the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- IHC - Frozen
- Immunofluorescence
- Western blot
- Immunoprecipitation
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GAPDH
Validation
Human Kidney: Formalin Fixed, Paraffin Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin Fixed, Paraffin Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
See More About...
LSBio Ratings
IHC-plus™ GAPDH Antibody (clone 6C5) for IHC, IF/Immunofluorescence, WB/Western, IP, ELISA LS-B11003 has an LSBio Rating of
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/27/2024
Date Requested: 4/27/2024
