Mouse Monoclonal [clone 9G6] (IgG1,k) to Human TTR / Transthyretin
IHC - Paraffin, Western blot, Immunoprecipitation
Human TTR / Transthyretin
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [9G6]
IHC - Paraffin (1:100), Western blot (1:2000), Immunoprecipitation
Specificity and Use
TTR / Transthyretin antibody was raised against protein purified from Human plasma.
Immunohistochemistry: LS-B2595 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2595 was determined to be 1:100.
HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
Prealbumin, also known as transethrytin (TTR) is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic.