Human TNF Alpha

Goat

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Purified

Unmodified

Recombinant human TNF-alpha.

Recognizes human Tumour Necrosis Factor alpha (TNFa€“alpha), a 17.4kD multi-functional pro-inflammatory cytokine primarily secreted by macrophages, but also produced by T and B lymphocytes, activated monocytes and fibroblasts. TNF-alpha exists in both a transmembrane and mature soluble form and has many biological properties, including activation of transcription factor NF-kappaB, the induction of apoptosis in various tumor cell lines and the stimulation of cell differentiation and proliferation under certain conditions. TNF-alpha also plays a role in inflammation, septic shock, autoimmune disease and rheumatoid arthritis.

• IHC - Paraffin
• Western blot (0.1 - 0.2 µg/ml)
• ELISA (0.25 - 1 µg/ml)

ELISA: May be used in an indirect ELISA or as a capture reagent in a sandwich ELISA.

PBS

100 µl Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.

Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P01375 NCBI: NM_000594 NP_000585.2