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Anti-PSEN1 / Presenilin 1 Antibody (aa431-467) LS-C191216

Ordering

Wt. Vol. Conc. Price
400 µg 400 µl - $740

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Rabbit Polyclonal (IgG) to Human PSEN1 / Presenilin 1
Human
ELISA
Unconjugated

Details

Human PSEN1 / Presenilin 1
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Purified

Applications

ELISA

Specificity and Use

PSEN1 / Presenilin 1 antibody was raised against synthetic peptide corresponding to aa431-467 of human Presenilin-1.
aa431-467
Human Presenilin-1.

Packaging

Lyophilized
400 µl Sterile distilled water
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C.
For research use only.

About PSEN1 / Presenilin 1

P49768 NM_000021 NP_000012.1

PSEN1 Antibody, AD3 Antibody, Alzheimer disease 3 Antibody, FAD Antibody, Protein S182 Antibody, PS1 Antibody, S182 Antibody, PS-1 Antibody, PSNL1 Antibody, Presenilin 1 Antibody, Presenilin-1 Antibody

Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP.

Requested From: United States
Date Requested: 7/28/2014
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