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Anti-MAP2K1 / MEK1 Antibody (phospho-Ser217) LS-C191025

Ordering

Wt. Vol. Conc. Price
50 µg - - $485

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Rabbit Polyclonal (IgG) to Human MAP2K1 / MEK1
Human, Mouse, Rat
IHC - Paraffin
Unconjugated

Details

Human MAP2K1 / MEK1
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Affinity purified

Applications

IHC - Paraffin (1:50 - 1:100)

Specificity and Use

MAP2K1 / MEK1 antibody was raised against synthetic phosphopeptide corresponding to human MEK1 around the phosphorylation site of serine 217 (I-D-SP-M-A).
pSer217
Human MEK1, phosphorylated at Ser217. Species Crossreactivity: mouse and rat.
Immunohistochemistry (formalin fixed paraffin embedded): 1:50-1:100.

Packaging

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at 12 months.
For research use only.

About MAP2K1 / MEK1

Q02750 NM_002755 NP_002746.1

MAP2K1 Antibody, ERK activator kinase 1 Antibody, MAPK/ERK kinase 1 Antibody, MAPKK 1 Antibody, MKK1 Antibody, PRKMK1 Antibody, MEK 1 Antibody, MAP kinase kinase 1 Antibody, MAPKK1 Antibody, MEK1 Antibody

MEK1, a MAP2K type protein kinase, is a member of the Ras MAPK pathway. This pathway modulates the activity of transcription factors, structural proteins and other protein kinases, leading to biological responses such as cell proliferation and differentiation. MEK1 contains a proline-rich segment that is recognized by the scaffold protein MEK binding partner-1 (MP1). MP1 associates with non-phosphorylated MEK1, forming a complex which associates with and phosphorylates MAP kinases ERK1 and 2.

Requested From: United States
Date Requested: 8/1/2014
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