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Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion. May use human CD46 and/or SLAMF1 as receptors for viral entry into the cell. The high degree of interaction between H and MCP/CD46 results in down-regulation of the latter from the surface of infected cells, rendering them more sensitive to c3b-mediated complement lysis.
Gene Name: | Hemagglutinin glycoprotein (HEMA) |
Synonyms: | HA, HEMA, Hemagglutinin |
Target Sequences: | P35971 P35971 |
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