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Anti-ATP13A2 Antibody (aa200-300) LS-C49134

Ordering

Wt. Vol. Conc. Price
- 100 µl 0.75 mg/ml $335

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206-374-1102
866-206-6909
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ATP13A2 Antibody LS-C49134 Images

[click image for a larger image and more details]
Immunohistochemistry
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry
Detection of ATP13A2 in mouse brain membrane lysate.
Western Blot
Detection of ATP13A2 in mouse brain membrane lysate.
 

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Rabbit Polyclonal to Human ATP13A2
Human, Mouse
IHC, IHC - Paraffin, Western blot
Unconjugated

Details

Human ATP13A2
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC (10 - 20 µg/ml), IHC - Paraffin (1:100), Western blot

Specificity and Use

ATP13A2 antibody was raised against a synthetic peptide within the internal region of residues 200-300 of the human ATP13A2 protein. [Swiss-Prot# Q9NQ11]
aa200-300
ATP13A2.

Packaging

Tris-glycine buffer, 150 mM sodium chloride, 0.05% sodium azide.
Long term: -70°C; Short term: -20°C
For research use only.

Publications (1)

1
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. Dehay B, Ramirez A, Martinez-Vicente M, Perier C, Canron MH, Doudnikoff E, Vital A, Vila M, Klein C, Bezard E. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:9611-6. (IHC, WB; Human) [PubMed:22647602] [PMC:PMC3386132]

About ATP13A2

Q9NQ11 NM_022089 NP_071372.1

ATP13A2 Antibody, HSA9947 Antibody, PARK9 Antibody, RP1-37C10.4 Antibody, Putative ATPase Antibody, ATPase type 13A2 Antibody, CLN12 Antibody, KRPPD Antibody

ATP13A2 belongs to the P-type superfamily of ATPases that transport inorganic cations and other substrates across cell membranes. ATP13A2 has predominantly neuronal expression and transiently transfected cells studies have shown that it is located in lysosomes. Recently a loss-of-function mutation in ATP13A2 has been linked to an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia.

Immunohistochemistry

Immunohistochemistry
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry

Immunohistochemistry
Detection of ATP13A2 in mouse brain membrane lysate.

Western Blot

Western Blot
Detection of ATP13A2 in mouse brain membrane lysate.
 

Requested From: United States
Date Requested: 7/28/2014
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