LSBio
Rat NT5E / eNT / CD73 Protein (Recombinant)

Rat NT5E / eNT / CD73 Protein (Recombinant)

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Expression SystemHuman Embryonic Kidney 293
Format:Lyophilized
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$283.00each
Catalog Number: LS-G137922-10

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Overview

Description
CD73, also known as Ecto-5'-nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor. The enzyme is expressed by most cell types. The 5'-Nucleotidase activity of CD73 converts extracellular nucleoside-5'-monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
5-nucleotidase | ecto (CD73) | 5'-nucleotidase | 5 nucleotidase (CD73) | 5-NT | CD73 | CD73 antigen | E5NT | Ecto-5-nucleotidase | ENT | EN | NT | Purine 5-Prime-Nucleotidase | NT5 | NT5E | NTE
Origin Species
Rat
NCBI GenBank
NM_002526
SwissProt
P21589

Protein

Expression System
Human Embryonic Kidney 293
Protein Type
Recombinant
Amino Acid Sequence
1WELTIMHTND VHSRLEQTSD DSTKCLNASL CVGGVARLFT KVQQIRKEEP NVLLLDAGDQ
61YQGTIWFTVY KGLEVAHFMN LLGYDAMALG NHEFDNGVEG LIDPLLRNVK FPILSANIKA
121RGPLAPQISG LYLPYKVLSV GGEVVGIVGY TSKETPFLSN PGTNLVFEDE VTALQPEVDK
181LKTLNVNKII ALGHSGFEMD KLIAQKVRGV DVVVGGHTNT FLYTGNPPSK EVPAGKYPFI
241VTSDDGRKVP VVQAYAFGKY LGYLKVEFDD KGNVVTSYGN PILLNSTIRE DAAIKADINQ
301WRIKLDNYST QELGRTIVYL NGSAQECRFR ECNMGNLICD AMINNNLRHP DEMFWNHVSM
361CIVNGGGIRS PIDERNNGTI TWENLAAVLP FGGTFDLVQL KGSTLKKAFE HSVHRYGQST
421GEFLQVGGIH VVYDISRKPW DRVVQLKVLC TKCRVPIYEP LEMDKVYKVV LPSYLVNGGD
481GFQMIKDELL KHDSGDQDIS VVSEYISKMK VIYPAVEGRI KVDHHHHHH

529 aa

Format

Purity
>90%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a sterile solution in PBS, pH 7.4.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.