LSBio
Rat IL12 Protein (Recombinant His)

Rat IL12 Protein (Recombinant His)

ProteinLSBio Guarantee
Expression SystemChinese Hamster Ovary
Format:Lyophilized
See all IL12 antibodies →
$302.00each
Catalog Number: LS-G27143-10

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Overview

Description
Interleukin-12 (IL-12), also known as NKSF, TCMF, CLMF and TSF, is a heterodimeric cytokine composed of p35 and p40 subunits. It is produced by monocytes, macrophages, B cells and dendritic cells in response to bacterial lipopolysaccharides and intracellular pathogens. IL-12 signals through the IL-12 receptor complex, which is comprised of IL-12 RBeta1 and IL-12 RBeta2. IL-12 induces the proliferation and activation of hematopoietic stem cells, natural killer cells and T- cells. It is indispensible during the development of Th1 cells, leading to the production of IFN-gamma and IL-2.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
IL-12 p70
Origin Species
Rat

Protein

Expression System
Chinese Hamster Ovary
Fusion Tag
Hexahistidine Tag
Molecular Weight
40 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1p35:RVIPVS GPAKCLNQSQ NLLKTTDDMV RTAREKLKHY SCTAGDIDHE DITRDKTSTL
61EACLPLELHK NESCLATKET SSIIRGSCLP PQKTSLMMTL CLGSIYEDLK MYQSEFQAIN
121AALQSHNHQQ ITLDRNMLMA IDELMRSLNH SGETLHQKAP MGEADPYRVK MKLCILLHAF
181STRVMTINRV MNYLSSSHHH HHHp40:MWE LEKDVYVVEV DWRPDAPGET VTLTCDSPEE
241DDITWTSDQR RGVIGSGKTL TITVREFLDA GQYTCHRGGE TLSHSHLLLH KKENGIWSTE
301ILKNFKNKTF LKCEAPNYSG RFTCSWLVHR NTDLKFNIKS SSSSPESRAV TCGRASLSAE
361KVTLNQRDYE KYSVACQEDV TCPTAEETLP IELVVEAQQQ NKYENYSTSF FIRDIIKPDP
421PKNLQVKPLK NSQVEVSWEY PDSWSTPHSY FSLKFFVRIQ RKKEKTKETE EECNQKGAFL
481VEKTSAEVQC KGANICVQAQ DRYYNSSCSK WTCVPCRGRS

520 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.