LSBio
Mouse THPO / TPO / Thrombopoietin Protein (Recombinant)

Mouse THPO / TPO / Thrombopoietin Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemChinese Hamster Ovary
Format:Lyophilized
See all THPO antibodies →
$302.00each
Catalog Number: LS-G27235-10

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Overview

Description
Thrombopoietin (TPO), also known as C-mpl ligand, MGDF and Thpo, is a glycoprotein hormone belonging to the EPO/TPO family. It is expressed mainly in the liver, kidney and skeletal muscle. TPO binds and signals through MLP/C_MPL receptor. It stimulates the proliferation and maturation of megakaryocytes from their committed progenitor cells, and it regulates the production and circulation of platelets. TPO has also been reported to promote the apoptosis of hypoxia-sensitized neurons and to inhibit neuronal differentiation.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
C-mpl ligand | MGDF | MPL ligand | THCYT1 | Thrombopoietin nirs variant 1 | MKCSF | THPO | MPLLG | Thrombopoietin
Origin Species
Mouse
NCBI GenBank
NM_000460|NP_000451.1
SwissProt
P40225

Protein

Expression System
Chinese Hamster Ovary
Molecular Weight
30-80 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA
61QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA
121HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKFPNRTSG
181LLETNFSVTA RTAGPGLLSR LQGFRVKITP GQLNQTSRSP VQISGYLNRT HGPVNGTHGL
241FAGTSLQTLE ASDISPGAFN KGSLAFNLQG GLPPSPSLAP DGHTPFPPSP ALPTTHGSPP
301QLHPLFPDPS TTMPNSTAPH PVTMYPHPRN LSQET

335 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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