SHH / Sonic Hedgehog Antibody
Catalog Number: LS-C405795
4 sizes / from $260.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity: Human, Mouse, Rat
Format: Liquid
Mouse SHH / Sonic Hedgehog Protein (Recombinant)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Lyophilized |
$284.00each
Catalog Number: LS-G27074-10
Catalog Number: LS-G27074
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- Description
- Sonic Hedgehog (Shh) is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. In mammal, there are threerelatedHh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh). They share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93% identical). Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body. Recombinant mouse Sonic Hedgehog(rmShh) produced in E.coli is a single non-glycosylated polypeptide chain containing 176 amino acids. A fully biologically active molecule, rmShh,is obtained by chromatographic techniques with a molecular mass of 19.8kDa analyzed by reducing SDS-PAGE.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- HHG-1 | HLP3 | Sonic hedgehog | Sonic hedgehog homolog | MCOPCB5 | SHH | Sonic hedgehog protein | HHG1 | HPE3 | SMMCI | TPT | TPTPS
- Origin Species
- Mouse
- NCBI GenBank
- NM_000193|NP_000184.1
- SwissProt
- Q15465
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Molecular Weight
- 19.8 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1IVIGPGRGFG KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKITRNSE RFKELTPNYN61PDIIFKDEEN TGADRLMTQR CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY121EGRAVDITTS DRDRSKYGML ARLAVEAGFD WVYYESKAHI HCSVKAENSV AAKSGG
176 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.
