SERPINE2 / Nexin Antibody
Catalog Number: LS-C155759-100
100 µL (1 mg/mL) / $459.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse
Format: Liquid
Mouse SERPINE2 / Nexin Protein (Recombinant 10His, C-terminus)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$275.00each
Catalog Number: LS-G137915-10
Catalog Number: LS-G137915
For bulk orders or custom formulations:
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- Description
- Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice leads to progressive neuronal and motor dysfunction in these animals. It is also over-expressed in the majority of pancreatic carcinoma as well as gastric and colorectal cancer samples whereas it is weakly expressed in all normal pancreas and chronic pancreatitis tissue samples. Serpin E2 is a potent inhibitor of thrombin, trypsin, urokinase, plasmin and plasminogen activators. It plays an important role in controlling male fertility because its knockout male mice show a marked impairment in fertility from the onset of sexual maturity and its abnormal expression is found in the semen of men with seminal dysfunction.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- GDNPF | GDN | PNI | PN1 | Protease nexin I | SERPINE2 | Nexin | Protease nexin 1 | Serpin E2 | Glia-derived nexin | Peptidase inhibitor 7 | PI-7 | PI7 | PN-1
- Origin Species
- Mouse
- NCBI GenBank
- A03911
- SwissProt
- P07093
Protein
- Expression System
- Other
- Fusion Tag
- Decahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
1SQFNSLSLEE LGSNTGIQVF NQIIKSRPHE NVVVSPHGIA SILGMLQLGA DGKTKKQLST61VMRYNVNGVG KVLKKINKAI VSKKNKDIVT VANAVFLRNG FKMEVPFAVR NKDVFQCEVQ121NVNFQDPASA SESINFWVKN ETRGMIDNLL SPNLIDGALT RLVLVNAVYF KGLWKSRFQP181ESTKKRTFVA GDGKSYQVPM LAQLSVFRSG STRTPNGLWY NFIELPYHGE SISMLIALPT241ESSTPLSAII PHITTKTIDS WMNTMVPKRM QLVLPKFTAV AQTDLKEPLK ALGITEMFEP301SKANFTKITR SESLHVSHIL QKAKIEVSED GTKASAATTA ILIARSSPPW FIVDRPFLFS361IRHNPTGAIL FLGQVNKPHH HHHHHHHH
388 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Sterile solution in 20 mM Tris, pH 8.0, 150 mM NaCl
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Store at < -20°C for up to 6 months. Avoid freeze-thaw cycles.
