LSBio
Mouse NOG / Noggin Protein (Recombinant)

Mouse NOG / Noggin Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemChinese Hamster Ovary
Format:Lyophilized
See all NOG antibodies →
$259.00each
Catalog Number: LS-G27138-5

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Overview

Description
Noggin, also known as NOG, is a homodimeric glycoprotein that binds to and modulates the activity of TGF-beta family ligands. It is expressed in condensing cartilage and immature chondrocytes. Noggin antagonizes bone morphogenetic protein (BMP) activities by blocking epitopes on BMPs needed for binding to their receptors.Noggin has been shown to be involved in many developmental processes, such as neural tube formation and joint formation. During development, Noggin diffuses through extracellular matrices and forms morphogenic gradients that regulate cellular responses in a concentration-dependent manner.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
NOG | Symphalangism 1 (proximal) | SYNS1 | SYM1 | Noggin
Origin Species
Mouse
NCBI GenBank
NM_005450|NP_005441.1
SwissProt
Q13253

Protein

Expression System
Chinese Hamster Ovary
Molecular Weight
29-31 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1LRAAPAGGQH YLHIRPAPSD NLPLVDLIEH PDPIFDPKEK DLNETLLRSL LGGHYDPGFM
61ATSPPEDRPG GGGGPAGGAE DLAELDQLLR QRPSGAMPSE IKGLEFSEGL AQGKKQRLSK
121KLRRKLQMWL WSQTFCPVLY AWNDLGSRFW PRYVKVGSCF SKRSCSVPEG MVCKPSKSVH
181LTVLRWRCQR RGGQRCGWIP IQYPIISECK CSC

213 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.