LSBio
Mouse IL12 Protein (Recombinant)

Mouse IL12 Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemChinese Hamster Ovary
Format:Lyophilized
See all IL12 antibodies →
$366.00each
Catalog Number: LS-G27144-10

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Overview

Description
Interleukin-12 (IL-12), also known as NKSF, TCMF, CLMF and TSF, is a heterodimeric cytokine composed of p35 and p40 subunits. It is produced by monocytes, macrophages, B cells and dendritic cells in response to bacterial lipopolysaccharides and intracellular pathogens. IL-12 signals throughtheIL-12 receptor complex, which is comprised of IL-12 RBeta1 and IL-12 RBeta2. IL-12 induces the proliferation and activation of hematopoietic stem cells, natural killer cells and T- cells. It is indispensible during the development of Th1 cells, leading to the production of IFN-gamma and IL-2.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
IL-12 p70
Origin Species
Mouse

Protein

Expression System
Chinese Hamster Ovary
Molecular Weight
40 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1p35Subunit :RVIPVSGPA RCLSQSRNLL KTTDDMVKTA REKLKHYSCT AEDIDHEDIT
61RDQTSTLKTC LPLELHKNES CLATRETSST TRGSCLPPQK TSLMMTLCLG SIYEDLKMYQ
121TEFQAINAAL QNHNHQQIIL DKGMLVAIDE LMQSLNHNGE TLRQKPPVGE ADPYRVKMKL
181CILLHAFSTR VVTINRVMGY LSSAp40Sub unit:MWELE KDVYVVEVDW TPDAPGETVN
241LTCDTPEEDD ITWTSDQRHG VIGSGKTLTI TVKEFLDAGQ YTCHKGGETL SHSHLLLHKK
301ENGIWSTEIL KNFKNKTFLK CEAPNYSGRF TCSWLVQRNM DLKFNIKSSS SSPDSRAVTC
361GMASLSAEKV TLDQRDYEKY SVSCQEDVTC PTAEETLPIE LALEARQQNK YENYSTSFFI
421RDIIKPDPPK NLQMKPLKNS QVEVSWEYPD SWSTPHSYFS LKFFVRIQRK KEKMKETEEG
481CNQKGAFLVE KTSTEVQCKG GNVCVQAQDR YYNSSCSKWA CVPCRVRS

528 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.