CD6 Antibody
Catalog Number: LS-C348352-0.1
0.1 mL / $325.00
Antibody: Mouse Monoclonal
Applications: Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin
Reactivity: Human
Format: Liquid
Mouse CD6 Protein (Recombinant 6His, C-terminus)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$253.00each
Catalog Number: LS-G137869-10
Catalog Number: LS-G137869
For bulk orders or custom formulations:
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- Description
- CD6 is a member of the group B scavenger receptor cysteinerich (SRCR) superfamily. CD6 is a type I membrane glycoprotein and contains three extracellular SRCR domains. CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subset of B cells, and a subset of neuronal cells express CD6. Mouse CD6 is a 626 amino acid (aa) protein with a 24 aa sequence, a 372 aa extracellular domain, and a 204 aa cytoplasmic region. The role of CD6 has not been fully elucidated. However, it appears to play a role as both a costimulatory molecule in T cell activation and as an adhesion receptor.CD6/ALCAM interactions have been postulated to play a role in thymocyte development. The CD6 intracellular domain contains regions that can interact with SH2 or SH3 containing proteins. However, the signaling pathways have not been elucidated.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- CD6 molecule | T12 | TP120 | CD6 | CD6 antigen
- Origin Species
- Ms
- NCBI GenBank
- NM_006725
- SwissProt
- P30203
Protein
- Expression System
- Other
- Fusion Tag
- 6×His
- Protein Type
- Recombinant
- Amino Acid Sequence
1LPSPAPSGQH KNGTIPNMTL DLEERLGIRL VNGSSRCSGS VKVLLESWEP VCAAHWNRAA61TEAVCKALNC GDSGKVTYLM PPTSELPPGA TSGNTSSAGN TTWARAPTER CRGANWQFCK121VQDQECSSDR RLVWVTCAEN QAVRLVDGSS RCAGRVEMLE HGEWGTVCDD TWDLQDAHVV181CKQLKCGWAV KALAGLHFTP GQGPIHRDQV NCSGTEAYLW DCPGRPGDQY CGHKEDAGVV241CSEHQSWRLT GGIDSCEGQV EVYFRGVWST VCDSEWYPSE AKVLCRSLGC GSAVARPRGL301PHSLDGRMYY SCKGQEPALS TCSWRFNNSN LCSQSRAARV VCSGSQRHLN LSTSEVPSRV361PVTIESSVPV SVKDKDSQGH HHHHH
385 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconj
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Purity Measurement Method
- SDS-PAGE
Storage & Handling
- Storage Conditions
- Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
