CD39 Antibody
Catalog Number: LS-C484896-100
100 µL / $309.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay
Reactivity: Mouse
Format: Liquid
Mouse CD39 Protein (Recombinant 6His, C-terminus)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$275.00each
Catalog Number: LS-G137883-10
Catalog Number: LS-G137883
For bulk orders or custom formulations:
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- Description
- Ectonucleoside triphosphate diphosphohydrolase-1(NTPDase-1) is an integral membrane protein with an extracellular active site. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker. But it is also present on the surface of natural killer cells, T cells, and some endothelial cells. NTPDase1 hydrolyzes the β-and? phosphate residues of nucleotides, preferring ATP as the substrate. Through its hydrolysis of extracellular nucleotides, NTPDase-1 plays a role in the regulation of purinergic signaling. NTPDase-1 is involved in the processes of thromboregulation and vascular inflammation. The administration of soluble NTPDase-1 may have therapeutic applications for the treatment of some vascular and transplantation-associated diseases.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- ATPDase | CD39 | CD39 antigen | Ecto-apyrase | Ecto-ATPDase 1 | Ecto-ATP diphosphohydrolase 1 | Ecto-ATPase 1 | NTPDase-1 | ENTPD1 | NTPDase 1
- Origin Species
- Ms
- NCBI GenBank
- NM_001776
- SwissProt
- P49961
Protein
- Expression System
- Other
- Fusion Tag
- 6×His
- Protein Type
- Recombinant
- Amino Acid Sequence
1TQNKPLPENV KYGIVLDAGS SHTNLYIYKW PAEKENDTGV VQQLEECQVK GPGISKYAQK61TDEIGAYLAE CMELSTELIP TSKHHQTPVY LGATAGMRLL RMESEQSADE VLAAVSTSLK121SYPFDFQGAK IITGQEEGAY GWITINYLLG RFTQEQSWLS LISDSQKQET FGALDLGGAS181TQITFVPQNS TIESPENSLQ FRLYGEDYTV YTHSFLCYGK DQALWQKLAK DIQVSSGGVL241KDPCFNPGYE KVVNVSELYG TPCTKRFEKK LPFDQFRIQG TGDYEQCHQS ILELFNNSHC301PYSQCAFNGV FLPPLHGSFG AFSAFYFVMD FFKKVAKNSV ISQEKMTEIT KNFCSKSWEE361TKTSYPSVKE KYLSEYCFSG AYILSLLQGY NFTDSSWEQI HFMGKIKDSN AGWTLGYMLN421LTNMIPAEQP LSPPLPHSTY IHHHHHH
447 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconj
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Purity Measurement Method
- SDS-PAGE
Storage & Handling
- Storage Conditions
- Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
