LSBio
Mouse CD38 Protein (Recombinant Fc, C-terminus)

Mouse CD38 Protein (Recombinant Fc, C-terminus)

ProteinLSBio Guarantee
Expression SystemOther
Format:Lyophilized
See all CD38 antibodies →
$253.00each
Catalog Number: LS-G137864-10

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Overview

Description
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
ADP-ribosyl cyclase 1 | CD38 antigen (p45) | CD38 antigen | Cyclic ADP-ribose hydrolase 1 | T10 | CADPr hydrolase 1 | CD38 | CD38 molecule | NAD(+) nucleosidase
Origin Species
Ms
NCBI GenBank
NM_001775
SwissProt
P28907

Protein

Expression System
Other
Fusion Tag
hFc
Protein Type
Recombinant
Amino Acid Sequence
1LRPRSLLVWT GEPTTKHFSD IFLGRCLIYT QILRPEMRDQ NCQEILSTFK GAFVSKNPCN
61ITREDYAPLV KLVTQTIPCN KTLFWSKSKH LAHQYTWIQG KMFTLEDTLL GYIADDLRWC
121GDPSTSDMNY VSCPHWSENC PNNPITVFWK VISQKFAEDA CGVVQVMLNG SLREPFYKNS
181TFGSVEVFSL DPNKVHKLQA WVMHDIEGAS SNACSSSSLN ELKMIVQKRN MIFACVDNYR
241PARFLQCVKN PEHPSCRLNT VDDIEGRMDE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK
301PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL
361TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT
421CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS
481VMHEALHNHY TQKSLSLSPG K

501 aa

Format

Purity
>95%
Conjugate/Label
Unconj
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a sterile solution in 20 mM PB, pH 7.0, 150 mM NaCl
Purity Measurement Method
SDS-PAGE

Storage & Handling

Storage Conditions
Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.