LSBio
Mouse Basigin / Emmprin / CD147 Protein (Recombinant 6His, C-terminus)

Mouse Basigin / Emmprin / CD147 Protein (Recombinant 6His, C-terminus)

ProteinLSBio Guarantee
Expression SystemOther
Format:Lyophilized
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$283.00each
Catalog Number: LS-G139305-10

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Overview

Description
Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
5F7 | Basigin | Basigin (Ok blood group) | CD147 antigen | BSG | EMMPRIN | OK | OK blood group antigen | TCSF | CD147 | M6
Origin Species
Mouse
NCBI GenBank
NM_001728
SwissProt
P35613

Protein

Expression System
Other
Fusion Tag
Hexahistidine Tag
Molecular Weight
34.1 kDa
Protein Type
Recombinant
Amino Acid Sequence
1Ala22-Arg3 25

12 aa

Format

Purity
>90%
Conjugate/Label
Unconjugated
Endotoxin Level
< 1.0 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a sterile solution in PBS, pH 7.4.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Long term: store at -20°C to -80°C for up to Lyophilized store for up to 12 months. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted store at less than -20°C for 3 months

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