LSBio
Human TNFRSF1A / TNFR1 Protein (Recombinant)

Human TNFRSF1A / TNFR1 Protein (Recombinant)

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Expression SystemChinese Hamster Ovary
Format:Lyophilized
See all TNFRSF1A antibodies →
$284.00each
Catalog Number: LS-G27178-10

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Overview

Description
TNF Receptor Type I, is also known as TNF R-p55/p60 and TNFRSF1A. It is a type I transmembrane protein member of the TNF receptor superfamily. It is expressed in most cell types. Binding of either TNF-a or TNF-beta to TNF-R1 initiates a signal transduction pathway that results in the activation of the transcription factor NF-kappaB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells, induce apoptosis. TNF-R1 is essential for proper development of lymph node germinal centers and Peyer's patches and for combating intracellular pathogens such as Listeria. It is stored in the Golgi and translocates to the cell surface following proinflammatory stimuli.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
CD120a | CD120a antigen | MS5 | p60 | TBP1 | TNF-R55 | TNFAR | TNFR1 | p55-R | TNF-R | TNF-R-I | TNF-R1 | TNF-RI | Tnfr | TNFR-I | TNFR1-d2 | TNFR60 | TNFRSF1A | FPF | p55 | Tbpi | TNFR55
Origin Species
Human
NCBI GenBank
NM_001065|NP_001056.1
SwissProt
P19438

Protein

Expression System
Chinese Hamster Ovary
Molecular Weight
28~35 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD CRECESGSFT ASENHLRHCL
61SCSKCRKEMG QVEISSCTVD RDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE
121KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQIE N

161 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.