LSBio
Human TMPRSS2 / Epitheliasin Protein (Recombinant 6His, N-terminus)

Human TMPRSS2 / Epitheliasin Protein (Recombinant 6His, N-terminus)

ProteinLSBio Guarantee
Expression SystemYeast
Format:Liquid
See all TMPRSS2 antibodies →
$372.00each
Catalog Number: LS-G57269-20

For bulk orders or custom formulations:

Request a Quote

Overview

Description
TMPRSS2 / Epitheliasin Protein LS-G57269 is a Recombinant Human TMPRSS2 / Epitheliasin produced in Yeast aa 106-492 with 6His, N-terminus tag(s). For Research Use Only
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Epitheliasin | PRSS10 | Serine protease 10 | PP9284 | TMPRSS2 | host protease for SARS-CoV-2 replication
Origin Species
Hu
NCBI GenBank
NM_005656
SwissProt
O15393

Protein

Expression System
Yeast
Fusion Tag
6×His
Protein Type
Recombinant
Amino Acid Sequence
1aa 106-492 |WKFMGSKCS NSGIECDSSG TCINPSNWCD GVSHCPGGED ENRCVRLYGP
61NFILQVYSSQ RKSWHPVCQD DWNENYGRAA CRDMGYKNNF YSSQGIVDDS GSTSFMKLNT
121SAGNVDIYKK LYHSDACSSK AVVSLRCIAC GVNLNSSRQS RIVGGESALP GAWPWQVSLH
181VQNVHVCGGS IITPEWIVTA AHCVEKPLNN PWHWTAFAGI LRQSFMFYGA GYQVEKVISH
241PNYDSKTKNN DIALMKLQKP LTFNDLVKPV CLPNPGMMLQ PEQLCWISGW GATEEKGKTS
301EVLNAAKVLL IETQRCNSRY VYDNLITPAM ICAGFLQGNV DSCQGDSGGP LVTSKNNIWW
361LIGDTSWGSG CAKAYRPGVY GNVMVFTDWI YRQMRADG

398 aa

Format

Purity
>90%
Conjugate/Label
Unconj
Endotoxin Level
Not Tested
Format
Liquid
Formulation
Lyophilized from 20mM Tris-HCl, pH 8.0, 0.5M NaCl, 6% Trehalose
Purity Measurement Method
SDS-PAGE

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity10 Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Member of Fraunhofer International Consortium for Anti-Infective Research (iCAIR), Nikolai-Fuchs-Strasse 1, 30625 Hannover, Germany12 Discovery Technology Rese. Markus Hoffmann, Heike Hofmann-Winkler, Joan C Smith, Nadine Krüger, Prerna Arora, Lambert K Sørensen, Ole S Søgaard, Jørgen Bo Hasselstrøm, Michael Winkler, Tim Hempel, Lluís Raich, Simon Olsson, Olga Danov, Danny Jonigk, Takashi Yamazoe, Katsura Yamatsuta, Hirotaka Mizuno, Stephan Ludwig, Frank Noé, Mads Kjolby, Armin Braun, Jason M Sheltzer, Stefan Pöhlmann. EBioMedicine. 2021 Mar;;65:103255. PubMed: 33676899 PMC: PMC7930809
Submit a Publication

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.