LSBio
Human TGFA / TGF Alpha Protein (Recombinant)

Human TGFA / TGF Alpha Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemChinese Hamster Ovary
Format:Lyophilized
See all TGFA antibodies →
$244.00each
Catalog Number: LS-G27211-5

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Overview

Description
Protransforming Growth Factor-alpha (TGF-alpha), also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. It is expressed in monocytes, brain cells, keratinocytes and various tumor cells. ProTGF-alpha signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells. It may function as either a membrane-bound ligand or a soluble ligand. Membrane-bound proTGF-alpha plays a role in cell-cell adhesion and juxtacrine stimulation of adjacent cells. The soluble form of the cytokine is released from the membrane-bound form by proteolytic cleavage and acts as a mitogen for cell proliferation.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Etgf | TGFA | TFGA | TGF Alpha | Tgf type 1 | TGF-alpha | Egf-like tgf
Origin Species
Human
NCBI GenBank
NM_003236|NP_003227.1
SwissProt
P01135

Protein

Expression System
Chinese Hamster Ovary
Molecular Weight
8-10 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA

50 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.