LSBio
Human PGAM2 Protein (Recombinant His)

Human PGAM2 Protein (Recombinant His)

Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
See all PGAM2 antibodies →
$267.00each
Catalog Number: LS-G1647-20

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Overview

Description
PGAM2, also known as phosphoglycerate mutase 2, belongs to the phosphoglycerate mutase family. Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. Recombinant human PGAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
BPG-dependent PGAM 2 | GSD10 | PGAMM | PGAM-M | PGAM2 | Phosphoglycerate mutase 2
Origin Species
Hu
SwissProt
P15259

Protein

Expression System
E.coli
Fusion Tag
6×His
Protein Type
Recombinant
Amino Acid Sequence
11-253aa|MG SSHHHHHHSS GLVPRGSHMA THRLVMVRHG ESTWNQENRF CGWFDAELSE
61KGTEEAKRGA KAIKDAKMEF DICYTSVLKR AIRTLWAILD GTDQMWLPVV RTWRLNERHY
121GGLTGLNKAE TAAKHGEEQV KIWRRSFDIP PPPMDEKHPY YNSISKERRY AGLKPGELPT
181CESLKDTIAR ALPFWNEEIV PQIKAGKRVL IAAHGNSLRG IVKHLEGMSD QAIMELNLPT
241GIPIVYELNK ELKPTKPMQF LGDEETVRKA MEAVAAQGKA K

281 aa

Format

Purity
>95%
Conjugate/Label
Unconj
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT.
Purity Measurement Method
SDS-PAGE

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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