LSBio
Human PCNA Protein (Recombinant)

Human PCNA Protein (Recombinant)

Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
See all PCNA antibodies →
$267.00each
Catalog Number: LS-G3526-20

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Overview

Description
PCNA (Proliferating Cell Nuclear Antigen) is found in the nucleus and is a cofactor of DNA polymerase delta. This protein is associated with DNA synthesis and repair. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. It appears during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA may be induced by uV irradiation, growth factors and eventually by neighbouring tumours. Recombinant human PCNA, was expressed in E.coli and purified by conventional chromatography techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
Cyclin | PCNA
Origin Species
Human
SwissProt
P12004

Protein

Expression System
Escherichia coli (Prokaryotic)
Protein Type
Recombinant
Amino Acid Sequence
11-261aa|MF EARLVQGSIL KKVLEALKDL INEACWDISS SGVNLQSMDS SHVSLVQLTL
61RSEGFDTYRC DRNLAMGVNL TSMSKILKCA GNEDIITLRA EDNADTLALV FEAPNQEKVS
121DYEMKLMDLD VEQLGIPEQE YSCVVKMPSG EFARICRDLS HIGDAVVISC AKDGVKFSAS
181GELGNGNIKL SQTSNVDKEE EAVTIEMNEP VQLTFALRYL NFFTKATPLS STVTLSMSAD
241VPLVVEYKIA DMGHLKYYLA PKIEDEEGS

269 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
20mM Tris-HCl buffer, pH 7.5, 2mM EDTA, 20% glycerol
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.