NQO1
Catalog Number: LS-C100530-400
400 µL / $401.00
Antibody: Rabbit Polyclonal
Applications: Flow Cytometry, Immunofluorescence, Western Blot
Reactivity: Human
Format: Liquid
Human NQO1 Protein (Recombinant His)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Liquid |
$318.00each
Catalog Number: LS-G615-20
Catalog Number: LS-G615
For bulk orders or custom formulations:
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- Description
- NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This protein apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 functions as an important part of cellular antioxidant defense by detoxifying quinines thus preventing the formation of reactive oxygen species. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer's disease (AD). Recombinant NQO1 protein was expressed in E.coli and purified by using conventional chromatography techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- Azoreductase | DHQU | DT-diaphorase | Dioxin-inducible 1 | DIA4 | Diaphorase-4 | NAD(P)H:quinone oxireductase | Phylloquinone reductase | QR1 | Menadione reductase | NMOR1 | NMORI | NQO1 | DTD | Quinone reductase 1
- Origin Species
- Human
- NCBI GenBank
- NM_000903|NP_000894.1
- SwissProt
- P15559
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
11-274aa|Se quencesofa minoacids: MGSSHHHHHH SSGLVPRGSH MVGRRALIVL61AHSERTSFNY AMKEAAAAAL KKKGWEVVES DLYAMNFNPI ISRKDITGKL KDPANFQYPA121ESVLAYKEGH LSPDIVAEQK KLEAADLVIF QFPLQWFGVP AILKGWFERV FIGEFAYTYA181AMYDKGPFRS KKAVLSITTG GSGSMYSLQG IHGDMNVILW PIQSGILHFC GFQVLEPQLT241YSIGHTPADA RIQILEGWKK RLENIWDETP LYFAPSSLFD LNFQAGFLMK KEVQDEEKNK301KFGLSVGHHL GKSIPTDNQI KARK
324 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- Not Tested
- Format
- Liquid
- Formulation
- 20 mM Tris-HCl, pH 8.0, 1 mM DTT, 10% Glycerol
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
