LSBio
Human LDLR / LDL Receptor Protein (Recombinant His,C-terminus)

Measure by its ability to bind with human PCSK9 in a functional ELISA. Immobilized human PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated recombinant human LDLR. The EC50 of biotinylated human LDLR is 0.61 µg/ml.

Human LDLR / LDL Receptor Protein (Recombinant His,C-terminus)

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Expression SystemHuman Embryonic Kidney 293
Format:Lyophilized
See all LDLR antibodies →
$372.00each
Catalog Number: LS-G48798-50

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Overview

Description
LDLR / LDL Receptor Protein LS-G48798 is a Recombinant Human LDLR / LDL Receptor produced in HEK 293 Cells Met1-Arg788 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
FHC | LDL receptor | LDLCQ2 | LDLR
Origin Species
Hu
NCBI GenBank
NM_000527
SwissProt
P01130

Protein

Expression System
HEK293
Fusion Tag
6×His
Molecular Weight
The secreted recombinant human LDLR comprises 777 amino acids with a predicted molecular mass of 86 kDa. As a result of different glycosylation, it migarates with the apparent molecular mass of 110-140 kDa in SDS-PAGE under reducing conditions corresponding to the mature and immature form.
Protein Type
Recombinant
Amino Acid Sequence
1Met1-Arg78 8

11 aa

Format

Purity
>85%
Conjugate/Label
Unconj
Endotoxin Level
< 1.0 EU/µg
Format
Lyophilized
Formulation
Lyophilized from sterile PBS, pH 7.4, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Purity Measurement Method
SDS-PAGE

Storage & Handling

Storage Conditions
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.