LSBio
Human IL2RA / CD25 Protein (Recombinant His, N-Terminal)

Human IL2RA / CD25 Protein (Recombinant His, N-Terminal)

ProteinLSBio Guarantee
Expression SystemHuman Embryonic Kidney 293
Format:Lyophilized
See all IL2RA antibodies →
$279.00each
Catalog Number: LS-G26995-10

For bulk orders or custom formulations:

Request a Quote

Overview

Description
Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to the cytokine IL-2. The IL-2R is made up of 3 subunits - alpha, beta and gamma. The a and beta chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the gamma-chain, along with the beta subunit. The beta and gamma chains of the IL-2R are members of the type I cytokine receptor family. IL-2R has a high binding affinity to IL-2 and is expressed by antigen-activated T lymphocytes (T cells). IL-2 Ra is also known as CD25, p55, and Tac (activated T cell) antigen. Recombinant Human Interleukin-2 Receptor a (IL-2 R a), His produced in HEK 293 cells is a polypeptide chain containing 205 amino acids. A fully biologically active molecule, rhIL-2 R a has a molecular mass of 42 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
CD25 antigen | CD25 | IDDM10 | IL-2 receptor subunit alpha | IL2R | Interleukin 2 receptor | alpha | IL-2-RA | IL2-RA | IL2RA | TCGFR | IL-2R subunit alpha | p55 | TAC antigen
Origin Species
Human
NCBI GenBank
NM_000417|NP_000408.1
SwissProt
P01589

Protein

Expression System
Human Embryonic Kidney 293
Fusion Tag
Hexahistidine Tag
Molecular Weight
42 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1HHHHHHHHEL CDDDPPEIPH ATFKAMAYKE GTMLNCECKR GFRRIKSGSL YMLCTGNSSH
61SSWDNQCQCT SSATRNTTKQ VTPQPEEQKE RKTTEMQSPM QPVDQASLPG HCREPPPWEN
121EATERIYHFV VGQMVYYQCV QGYRALHRGP AESVCKMTHG KTRWTQPQLI CTGEMETSQF
181PGEEKPQASP EGRPESETSC

200 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 3 months.

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.