IL17RA Antibody
Catalog Number: LS-C487369-100
100 µL / $309.00
Antibody: Mouse Monoclonal
Applications: Western Blot
Reactivity: Human
Format: Liquid
Human IL17RA Protein (Recombinant 6His, C-terminus)
ProteinLSBio Guarantee
| Expression System | Other |
| Format: | Lyophilized |
$253.00each
Catalog Number: LS-G137898-10
Catalog Number: LS-G137898
For bulk orders or custom formulations:
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- Description
- CD217, also known as Interleukin-17 receptor A, is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F, it binds to IL17A with higher affinity than to IL17F and binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. It also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. The activation of IL17RA would lead to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6. The signaling events of IL 17 includes activation of NF kappa B and JNK, and require TNF receptor associated factors 6 (TRAF6) in the signaling pathway.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- CANDF5 | CD217 antigen | CDw217 | CD217 | HIL-17R | IL-17RA | IL17R | Interleukin-17 receptor A | IL17RA | IL-17 receptor | IL-17 receptor A | Interleukin 17 receptor | Interleukin 17 receptor A
- Origin Species
- Human
- NCBI GenBank
- NM_014339
- SwissProt
- Q96F46
Protein
- Expression System
- Other
- Fusion Tag
- Hexahistidine Tag
- Protein Type
- Recombinant
- Amino Acid Sequence
1LRLLDHRALV CSQPGLNCTV KNSTCLDDSW IHPRNLTPSS PKDLQIQLHF AHTQQGDLFP61VAHIEWTLQT DASILYLEGA ELSVLQLNTN ERLCVRFEFL SKLRHHHRRW RFTFSHFVVD121PDQEYEVTVH HLPKPIPDGD PNHQSKNFLV PDCEHARMKV TTPCMSSGSL WDPNITVETL181EAHQLRVSFT LWNESTHYQI LLTSFPHMEN HSCFEHMHHI PAPRPEEFHQ RSNVTLTLRN241LKGCCRHQVQ IQPFFSSCLN DCLRHSATVS CPEMPDTPEP IPDYMPLWVD HHHHHH
296 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from a sterile solution in PBS, pH 7.4.
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
