IGFBP4 Antibody
Catalog Number: LS-C130050-100
100 µg / $878.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Human
Format: Lyophilized
Human IGFBP4 Protein (Recombinant His, C-Terminal)
ProteinLSBio Guarantee
| Expression System | Human Embryonic Kidney 293 |
| Format: | Lyophilized |
$268.00each
Catalog Number: LS-G27236-10
Catalog Number: LS-G27236
For bulk orders or custom formulations:
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- Description
- Insulin-like growth factor-binding protein 4 (IGF-BP-4), also known as IBP-4, is a secreted glycoprotein belonging to the IGFBP family. IGF-BP-4 is produced by osteoblasts, epidermis, ovarian follicles and other tissues. It binds both insulin-like growth factor (IGF) I and II, and it circulates in the plasma in both glycosylated and non-glycosylated forms. IGF-BP-4 prolongs the half-life of the IGFs and has been shown to inhibit or stimulate the growth-promoting effects of the IGFs. Pregnancy Associated Plasma Protein A (PAPP-A) proteolytically cleaves IGF-BP-4 and reduces its affinity to bind IGFs, and thus serves as an important regulator of IGF-BP-4 function.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- BP-4 | HT29-IGFBP | IGF-binding protein 4 | IGFBP4 | IBP-4 | IGFBP-4 | IBP4
- Origin Species
- Human
- NCBI GenBank
- NM_001552|NP_001543.2
- SwissProt
- P22692
Protein
- Expression System
- Human Embryonic Kidney 293
- Fusion Tag
- Hexahistidine Tag
- Molecular Weight
- 30-35 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1DEAIHCPPCS EEKLARCRPP VGCEELVREP GCGCCATCAL GLGMPCGVYT PRCGSGLRCY61PPRGVEKPLH TLMHGQGVCM ELAEIEAIQE SLQPSDKDEG DHPNNSFSPC SAHDRRCLQK121HFAKIRDRST SGGKMKVNGA PREDARPVPQ GSCQSELHRA LERLAASQSR THEDLYIIPI181PNCDRNGNFH PKQCHPALDG QRGKCWCVDR KTGVKLPGGL EPKGELDCHQ LADSFREHHH241HHH
243 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
