LSBio
Human IFN Gamma / Interferon Gamma Protein (Recombinant)

Human IFN Gamma / Interferon Gamma Protein (Recombinant)

ProteinLSBio Guarantee
Expression SystemChinese Hamster Ovary
Format:Lyophilized
See all IFNG antibodies →
$251.00each
Catalog Number: LS-G27071-10

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Overview

Description
Human Interferon gamma (hIFN-gamma) is a macrophage-activating factor and the lone member of Interferon type II. The active form of IFN-gamma is an antiparallel dimer that interacts with the receptor IFN-gammaR1 and sets off IFN-gamma/JAK/STAT pathway. IFN-gamma signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-gamma-induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-gamma is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
IFG | Immune interferon | IFI | Interferon gamma | IFN-gamma | IFNG | Interferon | gamma | IFNY
Origin Species
Human
NCBI GenBank
NM_000619|NP_000610.2
SwissProt
P01579

Protein

Expression System
Chinese Hamster Ovary
Molecular Weight
15-25 kDa (SDS-PAGE)
Protein Type
Recombinant
Amino Acid Sequence
1QDPYVKEAEN LKKYFNAGHS DVADNGTLFL GILKNWKEES DRKIMQSQIV SFYFKLFKNF
61KDDQSIQKSV ETIKEDMNVK FFNSNKKKRD DFEKLTNYSV TDLNVQRKAI HELIQVMAEL
121SPAAKTGKRK RSQMLFRGRR ASQ

143 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
< 0.2 EU/µg
Format
Lyophilized
Formulation
Lyophilized from PBS
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.