Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.5-3 µg/mL in the presence of 10 ng/ml Recombinant Human ctivin A.

Human FST / Follistatin Protein (Recombinant Human IgG Fc, C-terminus)

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Expression System	Human Embryonic Kidney 293
Format:	Lyophilized

$412.00each

Catalog Number: LS-G47742-50

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Overview

Description: FST / Follistatin Protein LS-G47742 is a Recombinant Human FST / Follistatin produced in HEK 293 Cells Met1-Trp344 with Human IgG Fc, C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Category: Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names: Activin-binding protein | Follistatin isoform FST317 | Follistatin | Fs | FST
Origin Species: Human
NCBI GenBank: NM_006350
SwissProt: P19883

Protein

Expression System: Human Embryonic Kidney 293
Fusion Tag: Human IgG1 Fc Tag
Molecular Weight: The secreted recombinant human FST/Fc is a disulfide-linked homodimer. The reduced monomer consists of 556 amino acids and has a predicted molecular mass of 61.7 kDa. As a result of glycosylation, rh FST/Fc monomer migrates as an approximately 70 kDa band in SDS-PAGE under reducing conditions.
Protein Type: Recombinant
Amino Acid Sequence

Format

Purity: >85%
Conjugate/Label: Unconjugated
Endotoxin Level: < 1.0 EU/µg
Format: Lyophilized
Formulation: Lyophilized from sterile PBS, pH 7.4, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Purity Measurement Method: SDS-PAGE (Coomassie Stain)