FGF2 / Basic FGF Antibody
Catalog Number: LS-C129065-200
200 µg / $778.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Reactivity: Human
Format: Lyophilized
Biological Activity FGF-basic, Human stimulates cell proliferation of Balb/3T3 cells. The ED 50 for this effect is less than 0.25ng/mL.
Human FGF2 / Basic FGF Protein (Recombinant)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Lyophilized |
$259.00each
Catalog Number: LS-G27190-10
Catalog Number: LS-G27190
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- Description
- Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. Like other FGF family members, bFGF has the Beta trefoil structure. In vivo, bFGF is produced by a variety of cells, including cardiomycotes, fibroblasts, and vascular cells. bFGF regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. bFGF can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. The angiogenic effects of bFGF can produce beneficial cardioprotection during acute heart injury.Recombinant human Fibroblast Growth Factor-basic (rhFGF-basic) produced in E. coli is a single non-glycosylated polypeptide chain containing 154 amino acids. A fully biologically active molecule, rhFGF-basic has a molecular mass of 17.1 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- Basic fibroblast growth factor | FGFB | Fibroblast growth factor 2 | FGF-2 | Prostatropin | BFGF | FGF2 | HBGF-2
- Origin Species
- Human
- NCBI GenBank
- NM_002006|NP_001997.5
- SwissProt
- P09038
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Molecular Weight
- 17.1 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK61LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT121SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
154 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.
