FCER2 / CD23 Antibody
Catalog Number: LS-C331726
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human
Format: Liquid
Human FCER2 / CD23 Protein (Recombinant)
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| Expression System | Escherichia coli (Prokaryotic) |
| Format: | Lyophilized |
$441.00each
Catalog Number: LS-G131384-20
Catalog Number: LS-G131384
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- Description
- CD23 is a calcium dependent transmembrane glycoprotein which is expressed in many cell types. The cytoplasmic region of the protein has two isoforms the 'a' isoform that participates in IgE-regulated endocytosis, and the 'b' isoform, which is involved in IgE-regulated phagocytosis. It has been found that there are at least four soluble forms of the CD23 protein (sCD23) all of which are produced by the activity of metallo/cysteine proteases. In addition to binding IgE, sCD23 have been shown to promote the activation and differentiation of B-cells and stimulate the release of pro-inflammatory cytokines from monocytes.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- CD23 antigen | CD23A | CLEC4J | CD23 | FCER2 | Fc-epsilon-RII | IGEBF | Lymphocyte IgE receptor | BLAST-2 | FCE2
- Origin Species
- Human
- NCBI GenBank
- NM_002002
- SwissProt
- P06734
Protein
- Expression System
- Escherichia coli (Prokaryotic)
- Molecular Weight
- ~19.5 kDa
- Protein Type
- Recombinant
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 1.0 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from Sterile Solution PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- The lyophilized protein is stable for up to 1 year at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2°C to 8°C for 1 month, or at -20°C for 6 months, with a carrier protein without detectable loss of activity. Avoid freeze/thaw cycles.
