CXCL4 / PF4 Antibody
Catalog Number: LS-C104447
2 sizes / from $364.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity: Human
Format: Lyophilized
Human CXCL4 / PF4 Protein (Recombinant)
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| Expression System | Human Embryonic Kidney 293 |
| Format: | Lyophilized |
$284.00each
Catalog Number: LS-G27122-10
Catalog Number: LS-G27122
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- Description
- Platelet factor 4, also known as CXCL4, is expressed in megakaryocytes and stored in the a-granules of platelets. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. Platelet factor 4 can be antiproliferative and antiangiogenic, at least in part via interfering with FGF2 and VEGF heparin binding and thus inhibiting their signaling. However, it can also be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
- Category
- Proteins & Peptides > Proteins > Recombinant Proteins
- Alternative Names
- C-X-C motif chemokine 4 | CXCL4 | Iroplact | Oncostatin-A | PF-4 | SCYB4 | PF4 | Platelet factor 4
- Origin Species
- Human
- NCBI GenBank
- NM_002619|NP_002610.1
- SwissProt
- P02776
Protein
- Expression System
- Human Embryonic Kidney 293
- Molecular Weight
- ~7.8 kDa (SDS-PAGE)
- Protein Type
- Recombinant
- Amino Acid Sequence
1aa32-101|E AEEDGDLQCL CVKTTSQVRP RHITSLEVIK AGPHCPTAQL IATLKNGRKI61CLDLQAPLYK KIIKKLLES
79 aa
Format
- Purity
- >95%
- Conjugate/Label
- Unconjugated
- Endotoxin Level
- < 0.2 EU/µg
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS
- Purity Measurement Method
- SDS-PAGE (Coomassie Stain)
Storage & Handling
- Storage Conditions
- Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
