Human CTSB / Cathepsin B Protein (Recombinant 6His, C-terminus)

Overview

Description

Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes

Category

Proteins & Peptides > Proteins > Recombinant Proteins

Alternative Names

Cathepsin B1 | Cathepsin B | Cathepsins B | CPSB | Cysteine protease | CTSB | Preprocathepsin B | APP secretase | APPS

Origin Species

Hu

NCBI GenBank

NM_001908

SwissProt

P07858