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Human CSF1R / CD115 / FMS Protein (Recombinant His,C-terminus)

Measured by its ability to inhibit the human CSF-induced proliferation of M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 6-30 µg/mL in the presence of 3 ng/ml Recombinant Human M-CSF.

Human CSF1R / CD115 / FMS Protein (Recombinant His,C-terminus)

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Expression SystemHuman Embryonic Kidney 293
Format:Lyophilized
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$355.00each
Catalog Number: LS-G47288-100

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Overview

Description
CSF1R / CD115 / FMS Protein LS-G47288 is a Recombinant Human CSF1R / CD115 / FMS produced in HEK 293 Cells Met1-Glu512 with His,C-terminus tag(s). It is biologically active and is low in endotoxin; Less than 1.0 EU/µg protein (determined by LAL method). For Research Use Only
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
CD115 antigen | CSF-1R | CSF1R | CSF-1-R | CSF-1 receptor | FMS | Fim-2 | FIM2 | FMS proto-oncogene | M-CSFR | HDLS | M-cfs receptor | C-FMS | CD115 | CSF1 receptor | CSFR | M-CSF-R | MCSF Receptor | Proto-oncogene c-Fms
Origin Species
Hu
NCBI GenBank
NM_005211
SwissProt
P07333

Protein

Expression System
HEK293
Fusion Tag
6×His
Molecular Weight
The recombinant human M-CSFR contains 504 amino acids after the removal of signal peptide with a calculated molecular mass of 56 kDa. As a result of glycosylation, it migrates as an approximately 85-95 kDa protein in SDS-PAGE under reducing conditions.
Protein Type
Recombinant
Amino Acid Sequence
1Met1-Glu51 2

11 aa

Format

Purity
>98%
Conjugate/Label
Unconj
Endotoxin Level
< 1.0 EU/µg
Format
Lyophilized
Formulation
Lyophilized from sterile PBS, pH 7.4, with 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Purity Measurement Method
SDS-PAGE

Storage & Handling

Storage Conditions
Aliquot and store at -20°C to -80°C for one year. Avoid repeated freeze-thaw cycles.

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.